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2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro

DOI: 10.1109/isbi.2009.5193098



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Nuclear Segmentation in Microscope Cell Images: A Hand-Segmented Dataset and Comparison of Algorithms

Journal article published in 2009 by Luís Pedro Coelho ORCID, Aabid Shariff, Robert F. Murphy
This paper is available in a repository.
This paper is available in a repository.

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Image segmentation is an essential step in many image analysis pipelines and many algorithms have been proposed to solve this problem. However, they are often evaluated subjectively or based on a small number of examples. To fill this gap, we hand-segmented a set of 97 fluorescence microscopy images (a total of 4009 cells) and objectively evaluated some previously proposed segmentation algorithms.We focus on algorithms appropriate for high-throughput settings, where only minimal user intervention is feasible.The hand-labeled dataset (and all software used to compare methods) is publicly available to enable others to use it as a benchmark for newly proposed algorithms.