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Wiley, Angewandte Chemie International Edition, 39(52), p. 10325-10329, 2013

DOI: 10.1002/anie.201303420

Wiley, Angewandte Chemie, 39(125), p. 10515-10519, 2013

DOI: 10.1002/ange.201303420

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Semiconducting Polymer Nanoprobe for in vivo Imaging of Reactive Oxygen and Nitrogen Species

Journal article published in 2013 by Kanyi Pu, Adam J. Shuhendler ORCID, Jianghong Rao
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Semiconducting polymer nanoparticles are utilized as a free-radical inert and light-harvesting nanoplatform for in vivo molecular imaging of reactive oxygen and nitrogen species (RONS). With its RONS-sensitive fluorescence, good biodistribution and passive targeting ability to leaky inflammatory vasculature, this nanoprobe permits detection of RONS in the microenvironment of spontaneous bacterial infection following systemic administration.