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Bangladesh Pharmacological Society, Bangladesh Journal of Pharmacology, 3(10), p. 584

DOI: 10.3329/bjp.v10i3.22844

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Phytochemical screening and diuretic activity of <i>Euphorbia granulata</i>

Journal article published in 2015 by Hammad Saleem ORCID, Irshad Ahmad ORCID, M. Shoaib Ali Gill ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The aim of this study was to evaluate diuretic activity of aqueous methanolic extract of Euphorbia granulate in rats. Albino rats were divided into five groups. Group I served as reference, Group II as standard and Group III, IV and V served as test. The three doses of extract (30, 50 and 100 mg/kg) were given to rats (i.p) in acute diuretic model. Furosemide (10 mg/kg i.p) was used as standard drug. The extract induced diuretic effects and induced electrolytes excretion in a dose-dependent manner when compared with control. The extract (100 and 50 mg/kg) significantly (p