Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 3(54), p. 1360-1362, 2010
DOI: 10.1128/aac.01138-09
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Acquisition of flucytosine, azole, and caspofungin resistance in Candida glabrata bloodstream isolates serially obtained from a hematopoietic stem cell transplant recipient.
Journal article published in 2009 by
Florence Chapeland-Leclerc 
,
G. Soci�,
Christophe Hennequin,
Nicolas Papon ,
Thierry Noël,
T. No�l,
Aurélie Girard,
Gérard Socié,
Patricia Ribaud,
Claire Lacroix
,
G. Soci�,
Christophe Hennequin,
Nicolas Papon ,
Thierry Noël,
T. No�l,
Aurélie Girard,
Gérard Socié,
Patricia Ribaud,
Claire Lacroix
This paper is made freely available by the publisher.
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Abstract
ABSTRACT We describe the acquisition of flucytosine, azole, and caspofungin resistance in sequential Candida glabrata bloodstream isolates collected from a bone marrow transplant patient with clinical failure. Point mutations in C. glabrata FUR1 ( CgFUR1 ) and CgFKS2 and overexpression of CgCDR1 and CgCDR2 were observed in resistant isolates.