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Lippincott, Williams & Wilkins, Neurology: Neuroimmunology and Neuroinflammation, 1(3), p. e194, 2016

DOI: 10.1212/nxi.0000000000000194

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Alemtuzumab long-term immunologic effect: Treg suppressor function increases up to 24 months

Journal article published in 2016 by Stefania De Mercanti, Simona Rolla, Angele Cucci, Valentina Bardina, Eleonora Cocco, Anton Vladic, Silva Soldo-Butkovic, Mario Habek, Ivan Adamec, Dana Horakova, Pietro Annovazzi, Francesco Novelli, Luca Durelli, Marinella Clerico
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

To analyze changes in T-helper (Th) subsets, T-regulatory (Treg) cell percentages and function, and mRNA levels of immunologically relevant molecules during a 24-month follow-up after alemtuzumab treatment in patients with relapsing-remitting multiple sclerosis (RRMS).