Background: The aim of this study was to examine videotaped simulation-based team training (SBTT) and debriefing experiences from the perspectives of nursing staff and physicians on one surgical inpatient unit. Method: A descriptive qualitative method was used to obtain straightforward and unembellished answers to questions of special relevance to practitioners and policy makers. Results: One overarching theme emerged, "Leadership Is Key." Several subthemes emerged, "Use Closed Loop Communication," "Clearly Defining Roles Is Important," and "Develop Situational Awareness and Mutual Support." Conclusion: SBTT and debriefing is an evolving educational strategy that encourages work-based learning, collaboration, and teamwork, and improves communication. This approach effectively teaches how to develop collaborative health care teams by providing a plan that builds on previous experiences and improves team performance. Future research should examine how SBTT and debriefing directly affects behavior in the clinical setting and whether it improves communication and outcomes (bench-to-bedside perspective).