Published in
American Chemical Society, Organic Letters, 24(12), p. 5760-5763, 2010
DOI: 10.1021/ol1026552
Links
Tools
Duboscic Acid: A Potent α-Glucosidase Inhibitor with an Unprecedented Triterpenoidal Carbon Skeleton from Duboscia macrocarpa
Journal article published in 2010 by
Pascal Wafo,
Ramsay S. T. Kamdem,
Zulfiqar Ali,
Shazia Anjum,
Shamsun Nahar Khan,
Afshan Begum,
Karsten Krohn,
Berhanu M. Abegaz,
Bonaventure T. Ngadjui,
Muhammad Iqbal Choudhary
This paper is available in a repository.
Full text: Download
Preprint: archiving allowed
- Must obtain written permission from Editor
- Must not violate ACS ethical Guidelines
Postprint:
archiving restricted
- Must obtain written permission from Editor
- Must not violate ACS ethical Guidelines
Published version:
archiving forbidden
Data provided by 
Abstract
Duboscic acid (1), a triterpenoid with a unique carbon backbone, was isolated from Duboscia macrocarpa Bocq. It is the first member of a new class of triterpenoids, for which the name "dubosane" is proposed. Duboscic acid has a potent α-glucosidase inhibition, and its structure was unambiguously deduced by a single-crystal X-ray diffraction study.