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Elsevier, Lancet

DOI: 10.1016/s0140-6736(16)00143-4

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Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Journal article published in 2016 by Liping Hou, Urs Heilbronner ORCID, Franziska Degenhardt, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Raffaella Ardau, Bárbara Arias, Lena Backlund, Claudio E. M. Banzato, Antoni Benabarre, Susanne Bengesser, Abesh Kumar Bhattacharjee, Joanna M. Biernacka, Armin Birner and other authors.
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Lithium is a first-line treatment in bipolar disorder, but individual response is variable. Previous studies have suggested that lithium response is a heritable trait. However, no genetic markers of treatment response have been reproducibly identified.