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American Society of Hematology, Blood, 15(125), p. 2344-2348, 2015

DOI: 10.1182/blood-2014-05-574111

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p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency

Journal article published in 2015 by Jad I. Belle, David Langlais ORCID, Jessica C. Petrov, Mercedes Pardo ORCID, Russell G. Jones, Philippe Gros, Anastasia Nijnik
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points Developmental defects and impairment in lymphopoiesis in Mysm1-knockout mice are the result of p53 activation. Loss of hematopoietic stem cell function and bone marrow failure in Mysm1-knockout mice are the result of p53 activation.