Published in
American Medical Association, JAMA Neurology, 11(71), p. 1394
DOI: 10.1001/jamaneurol.2014.1491
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Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease
Journal article published in 2014 by
Adam C. Naj,
Gyungah Jun 
,
Christiane Reitz,
Brian W. Kunkle,
William Perry,
Yo Son Park,
Gary W. Beecham,
Ruchita A. Rajbhandary,
Kara L. Hamilton-Nelson,
Li-San Wang,
John S. K. Kauwe,
Matthew J. Huentelman,
Amanda J. Myers,
Thomas D. Bird,
Bradley F. Boeve
and other authors.
,
Christiane Reitz,
Brian W. Kunkle,
William Perry,
Yo Son Park,
Gary W. Beecham,
Ruchita A. Rajbhandary,
Kara L. Hamilton-Nelson,
Li-San Wang,
John S. K. Kauwe,
Matthew J. Huentelman,
Amanda J. Myers,
Thomas D. Bird,
Bradley F. Boeve
and other authors.
This paper is made freely available by the publisher.
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Abstract
Because APOE locus variants contribute to risk of late-onset Alzheimer disease (LOAD) and to differences in age at onset (AAO), it is important to know whether other established LOAD risk loci also affect AAO in affected participants.