Royal Society of Chemistry, Chemical Communications, 93(48), p. 11464, 2012
DOI: 10.1039/c2cc36481f
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The T-Hg-T bond was utilized to cross-link two lateral loops of chair-type G-quadruplex DNA (G4-DNA) structures. Two out of five cross-linking geometries are able to increase the melting temperature and simultaneously reduce the polymorphism of the G4-DNA conformations.