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Royal Society of Chemistry, Chemical Communications, 93(48), p. 11464, 2012

DOI: 10.1039/c2cc36481f

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Mercury–thymine interaction with a chair type G-quadruplex architecture

Journal article published in 2012 by Nicole M. Smith ORCID, Samir Amrane ORCID, Frédéric Rosu, Valérie Gabelica ORCID, Jean-Louis Mergny ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

The T-Hg-T bond was utilized to cross-link two lateral loops of chair-type G-quadruplex DNA (G4-DNA) structures. Two out of five cross-linking geometries are able to increase the melting temperature and simultaneously reduce the polymorphism of the G4-DNA conformations.