Published in

Cell Press, Molecular Cell, 1(55), p. 1-3, 2014

DOI: 10.1016/j.molcel.2014.06.022

Links

Tools

Export citation

Search in Google Scholar

PML, SUMO, and RNF4: guardians of nuclear protein quality

Journal article published in 2014 by Anne Gärtner, Stefan Muller
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Orange circle
Postprint: archiving restricted
Red circle
Published version: archiving forbidden
Data provided by SHERPA/RoMEO

Abstract

In this issue of Molecular Cell, Guo et al. (2014) report that misfolded or aggregated nuclear proteins, such as pathogenic polyQ proteins, are cleared by a SUMO-dependent quality control pathway, which involves the E3 SUMO ligase PML and the SUMO-targeted ubiquitin ligase RNF4.