Royal Society of Chemistry, Organic and Biomolecular Chemistry, 16(5), p. 2555
DOI: 10.1039/b708635k
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A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity-selectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.