The resistivity (ρ) and the thermopower (S) of spinel-type compounds CuIr2S4 and CuIr2Se4 have been measured at temperatures from 2 to 900 K under magnetic field from 0 to 15 T. The thermopower of both compounds is positive in the metallic phase except for the low-temperature region in CuIr2Se4. It is also positive in the insulating state of CuIr2S4, implying p-type charge carriers, in agreement with the recent photoemission results. The low-temperature resistivity of CuIr2S4 is well described by Efros–Shklovskii variable-range hopping conductivity mechanism: ρ=ρ0exp[(T∗/T)1/2]. The most unusual feature of the transport is that the resistivity of both compounds in the metallic state reveals an activation type of the temperature dependence.