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Cell Press, Trends in Biotechnology, (19), p. 17-22

DOI: 10.1016/s0167-7799(01)00004-x

Cell Press, Trends in Biotechnology, 10(19), p. S17-S22

DOI: 10.1016/s0167-7799(01)01795-4

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Matching peptide mass spectra to EST and genomic DNA databases

This paper is available in a repository.
This paper is available in a repository.

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Abstract

The use of mass spectrometry data to search molecular sequence databases is a well-established method for protein identification. The technique can be extended to searching raw genomic sequences, providing experimental confirmation or correction of predicted coding sequences, and has the potential to identify novel genes and elucidate splicing patterns.