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Elsevier España, Laboratorio Clínico, 2(2), p. 65-72

DOI: 10.1016/j.labcli.2009.03.001

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Asociación entre la diabetes mellitus de tipo 1 y la enfermedad celíaca: 6 años de cribado serológico sistemático

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Abstract

IntroductionCeliac disease and type 1 diabetes mellitus are chronic diseases that share a genetic susceptibility, presence of organ specific autoantibodies and influence of environmental factors. According to a cross-sectional study performed in our hospital in 2001, 8.3% of diabetic patients have positive serological markers for celiac disease and 4.9% have a Marsh grade III intestinal lesion. With this background, we began systematic serological screening for CD on onset of type 1 diabetes. Our aim was to evaluate the results of this strategy, as well as characterizing the patients diagnosed with celiac disease.