Elsevier, Journal of Hepatology, 1(67), p. 1-4, 2017
DOI: 10.1016/j.jhep.2017.04.007
Elsevier, Journal of Hepatology, 4(66), p. 671-674, 2017
DOI: 10.1016/j.jhep.2017.01.015
Elsevier, Journal of Hepatology, 3(66), p. 469-472, 2017
DOI: 10.1016/j.jhep.2016.12.021
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The most efficient strategy to treat chronic liver disease including NAFLD is to remove the cause (i.e., hypocaloric diet and aerobic exercise in patients with NAFLD). Although aerobic exercise reduces liver fat and visceral adipose tissue, there are limited prospective studies assessing the effect of different exercise programs. The study from Keating et al. investigated the effects of different programs of aerobic exercise (low to moderate intensity, high volume vs. high intensity, low volume aerobic). The authors found that both aerobic exercise regimens reduced liver and visceral fat and VAT without significant weight loss. This important study supports that exercise should be advised, when possible, to patients with NAFLD. For patients unable to modify their lifestyle, targeted therapies are needed.