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Elsevier, Bioorganic and Medicinal Chemistry Letters, 3(11), p. 383-386

DOI: 10.1016/s0960-894x(00)00673-9

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Solid-phase synthesis of oligonucleotides containing a Bipyridine ligand at the 3′-3′ inversion of polarity site

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This paper is available in a repository.

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Abstract

The preparation of a solid support useful for the synthesis of oligonucleotides with a 3'-3' inversion of polarity, via a linker containing a chelating molecule, namely 2,2'-bipyridine, is described.