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The Journal of the Korean Academy of Periodontology, 3(39), p. 331

DOI: 10.5051/jkape.2009.39.3.331

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Induction of IL8 and reactive oxygen species in periodontal ligament cells by Aggregatibacter actinomycetemcomitans

Journal article published in 2009 by Yang-Sin Lee, Hong Gyu Park, Sung Whan Kim, Jeong-Heon Cha, Yun-Jung Yoo
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Interleukin (IL)-8 is one of pro-inflammatory cytokines. Reactive oxygen species (ROS) are reduced metabolites of O2. Aggregatibacter actinomycetemcomitans is one of representative periodontopathogens. To investigate the role of A. actinomycetemcomitans in IL-8 expression of periodontal ligament (PDL) cells, we estimated the production of IL-8 and ROS in A. actinomycetemcomitans treated PDL cells.