Transfer of KPC-2 Carbapenemase from Klebsiella pneumoniae to Escherichia coli in a Patient: First Case in Europe

Journal article published in 2011 by S. N. RichterORCID, I. Frasson, C. Bergo, S. Parisi, A. Cavallaro, G. Palu

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Publisher: American Society for Microbiology

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Abstract
The first case in Europe of Klebsiella pneumoniae carbapenemase (KPC) 2 transfer from K. pneumoniae to Escherichia coli in the same patient is described. KPC-positive plasmids from the two species were identical, indicating horizontal plasmid transfer. Selection of the KPC-producing E. coli strain was triggered by therapy with meropenem.