Palm pressed fiber (PPF) and cattle manure (CM) are the waste which can be managed properly by anaerobic co-digestion. The biogas production in co-digested PPF and CM at three volatile solids (VS) ratios of 3:1, 1:1, and 1:3 was investigated in a series of batch experiments at an organic loading rate of 30.0g VS/L under mesophilic (37±1°C) conditions. The highest daily biogas yield of PPF and CM only, was 90.0mL/g VSadded at day 12 and 23.4mL/g VSadded at day 7. For co-digestion of PPF/CM at mixing ratios of 3:1, 1:1 and 1:3, there were 93.6mL/g VSadded at day 11, 86.8 and 26.4mL/g VSadded at day 8. VS removal rate for PPF, CM, and co-digestion at mixing ratio of 3:1, 1:1, and 1:3 were 91.1%, 86.0% and 71.0%, respectively. The anaerobic digestion of PPF and CM and their co-digestion systems were stable in operation with low range of volatile fatty acids (VFA)/TIC (total inorganic carbon) of (0.035-0.091). The main volatile fatty acids were propionic, and iso-butyric acids for PPF, iso-butyric and n-butyric acids for CM. The VFAs and ammonium inhibition were not occurred. The modified Gompertz model can be used to perform a better prediction with a lower difference between the measured and predicted biogas yields. A VS ratio of 3:1 is recommended for practice.