Published in
Royal Society of Chemistry, Journal of Materials Chemistry, 14(21), p. 5219, 2011
DOI: 10.1039/c1jm10199d
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BN Nanospheres as CpG ODN Carriers for Activation of Toll-Like Receptor 9
Journal article published in 2011 by
Chunyi Zhi 
,
Wenjun Meng,
Tomohiko Yamazaki,
Yoshio Bando ,
Dmitri Golberg,
Chengchun Tang,
Nobutaka Hanagata
,
Wenjun Meng,
Tomohiko Yamazaki,
Yoshio Bando ,
Dmitri Golberg,
Chengchun Tang,
Nobutaka Hanagata
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Abstract
For the first time, we demonstrated BN nanospheres (BNNSs) can interact with biomolecules and deliver unmethylated cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) into cells to activate toll-like receptor 9 (TLR9), which is a very important process for therapy of cancers and allergy diseases.