Oxford University Press (OUP), International Journal of Epidemiology, 4(44), p. 1388-1396
DOI: 10.1093/ije/dyu277
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Background: The DNA methylation-based ‘epigenetic clock’ correlates strongly with chronological age, but it is currently unclear what drives individual differences. We examine cross-sectional and longitudinal associations between the epigenetic clock and four mortality-linked markers of physical and mental fitness: lung function, walking speed, grip strength and cognitive ability.