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2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)

DOI: 10.1109/isbi.2014.6867986

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Spatio-temporal registration of embryo images

Proceedings article published in 2014 by Léo Guignard, Christophe Godin, Ulla-Maj Fiuza, Lars Hufnagel, Patrick Lemaire, Grégoire Malandain ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Current imaging techniques can capture temporal sequences of 3D images with very high time resolution over several hours. Com- paring sequences covering the same time period opens the way to the study of developmental variability. Stitching together sequences captured from different embryos may help producing a sequence covering the whole development of the animal of interest. For this, it is necessary to align two sequences in both time and space. We present here a method to align two 3D+t time series, based on the detection and pairing of 3D+t landmarks. These landmarks, which correspond to periods of fast morphogenetic change, are de- duced from the analysis of the non-linear transformations that allow to co-register pairs of consecutive 3D images in each sequence.