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BioMed Central, Respiratory Research, 1(16), 2015

DOI: 10.1186/s12931-015-0273-8

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Childhood pneumonia increases risk for chronic obstructive pulmonary disease: the COPDGene study

Journal article published in 2015 by Lystra P. Hayden, Brian D. Hobbs, Robyn T. Cohen, Robert A. Wise ORCID, William Checkley, James D. Crapo, Craig P. Hersh, on behalf of the COPDGene Investigators
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Background Development of adult respiratory disease is influenced by events in childhood. The impact of childhood pneumonia on chronic obstructive pulmonary disease (COPD) is not well defined. We hypothesize that childhood pneumonia is a risk factor for reduced lung function and COPD in adult smokers. Methods COPD cases and control smokers between 45–80 years old from the United States COPDGene Study were included. Childhood pneumonia was defined by self-report of pneumonia at