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Public Library of Science, PLoS Medicine, 5(6), p. e1000077, 2009

DOI: 10.1371/journal.pmed.1000077

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Folic acid supplementation and spontaneous preterm birth: adding grist to the mill?

Journal article published in 2009 by Leonie K. Callaway, Paul B. Colditz, Nicholas M. Fisk ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Preterm birth is increasing, and complicates 12% of deliveries in the United States. It is the dominant cause of neonatal mortality. Preterm birth also accounts for one in three children with vision impairment, one in five with mental retardation, and almost half with cerebral palsy [1]. Babies born weighing under 2,500 g are at heightened risk in adulthood of diabetes and cardiovascular disease [1]. These short- and long-term sequelae make the prevention of preterm birth a public health priority.