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Springer Nature [academic journals on nature.com], European Journal of Human Genetics, 8(20), p. 857-862

DOI: 10.1038/ejhg.2012.17

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Genome-wide analysis of epistasis in body mass index using multiple human populations

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We surveyed gene–gene interactions (epistasis) in human body mass index (BMI) in four European populations (n5000). We conclude that genome-wide analysis of epistasis in multiple populations is an effective approach to provide new insights into the genetic regulation of BMI but requires additional efforts to confirm the findings.