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Springer Nature [academic journals on nature.com], Molecular Psychiatry, 3(16), p. 240-242, 2010

DOI: 10.1038/mp.2010.25

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Convergence of linkage, association and GWAS findings for a candidate region for bipolar disorder and schizophrenia on chromosome 4p

Journal article published in 2010 by A. Christoforou, K. A. McGhee, S. W. Morris, P. A. Thomson, S. Anderson, A. McLean, H. S. Torrance, A. MacLean, S. Le Hellard, D. StClair, B. S. Pickard, W. J. Muir, D. H. Blackwood, D. J. Porteous, K. L. Evans
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Several strong candidate genes and regions have been implicated in bipolar disorder (BP) and schizophrenia (SCZ) through linkage and association studies. These disorders have also recently been studied in genome-wide association studies (GWAS), identifying further putative candidate loci, albeit with lower levels of significance and reproducibility than in GWAS of other complex disorders.