Introduction: In cancer progression the development of distant metastases is the crucial adverse event.Focusing on colorectal cancer, the majority (70%) of patients develops metastasis in the liver. Within the BMBF-founded consortium MetastaSys the role of the mutational activation in the WNT pathway[for full text, please go to the a.m. URL] ; SeriesInformation ; 132. Kongress der Deutschen Gesellschaft für Chirurgie