Published in
Royal Society of Chemistry, RSC Chemical Biology, 10(5), p. 1010-1016, 2024
DOI: 10.1039/d4cb00138a
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Early-stage biosynthesis of phenalinolactone diterpenoids involves sequential prenylation, epoxidation, and cyclization
Journal article published in 2024 by
Tyler A. Alsup 
,
Zining Li ,
Caitlin A. McCadden ,
Annika Jagels ,
Diana P. Łomowska-Keehner ,
Erin M. Marshall ,
Liao-Bin Dong ,
Sandra Loesgen ,
Jeffrey D. Rudolf
,
Zining Li ,
Caitlin A. McCadden ,
Annika Jagels ,
Diana P. Łomowska-Keehner ,
Erin M. Marshall ,
Liao-Bin Dong ,
Sandra Loesgen ,
Jeffrey D. Rudolf
This paper is made freely available by the publisher.
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Abstract
The first key steps in the biosynthesis of the phenalinolactones were investigated using heterologous expression of four core genes that are conserved in this family of bacterial meroterpenoids.