Dissemin is shutting down on January 1st, 2025

Published in

Wiley Open Access, Clinical Cardiology, 12(46), p. 1530-1537, 2023

DOI: 10.1002/clc.24142

Links

Tools

Export citation

Search in Google Scholar

Association between frailty and physical performance in older patients with heart failure

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

Full text: Download

Green circle
Preprint: archiving allowed
Green circle
Postprint: archiving allowed
Green circle
Published version: archiving allowed
Data provided by SHERPA/RoMEO

Abstract

AbstractBackgroundFrailty is an issue in patients with heart failure (HF). A Korean version of the frailty scale (K‐FRAIL) has been developed.HypothesisWe aimed to analyze the relationship between the K‐FRAIL scale and physical performance in patients with HF.MethodsThis study included 142 patients with HF aged ≥65 years from a single center. Muscular fitness was assessed using the handgrip test and knee extensor strength measurement. Aerobic capacity was assessed using the cardiopulmonary exercise test and 6‐min walk test (6MWT). Frailty was assessed using the K‐FRAIL questionnaire.ResultsPeak VO2 and 6MWT scores significantly decreased as frailty worsened, but handgrip and knee extensor strength did not. In the multivariate analysis, peak VO2 (β = −.31; p = .002) and 6MWT score (β = −.38; p < .001) showed significant inverse associations with the K‐FRAIL score. Based on the receiver operating characteristic curve analysis, the cut‐off values of peak VO2 (hazard ratio, 5.08; p = .023) and 6MWT (hazard ratio, 3.99; p = .020) were independent predictors of frailty.ConclusionIn older patients with HF, physical performance correlates with the degree of frailty. The K‐FRAIL scale is correlated with the peak VO2 and 6MWT.