Published in
Royal Society of Chemistry, RSC Medicinal Chemistry, 6(13), p. 731-736, 2022
DOI: 10.1039/d2md00064d
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Encoding BRAF inhibitor functions in protein degraders
Journal article published in 2022 by
Daniel S. J. Miller,
Sabine A. Voell 
,
Izidor Sosič ,
Matic Proj ,
Olivia W. Rossanese,
Gregor Schnakenburg,
Michael Gütschow ,
Ian Collins,
Christian Steinebach
,
Izidor Sosič ,
Matic Proj ,
Olivia W. Rossanese,
Gregor Schnakenburg,
Michael Gütschow ,
Ian Collins,
Christian Steinebach
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Novel BRAFV600E PROTACs were developed that maintain target degradation while sparing paradoxical activation of the MAPK pathway in BRAFwt cells.