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SAGE Publications, Nutrition and Health, p. 026010602211441, 2022

DOI: 10.1177/02601060221144140

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Study of metabolic syndrome indicators in newly diagnosed diabetes mellitus type 2 patients in Pakistani population

Journal article published in 2022 by Hajra Ahmad, Zaheer Ahmed ORCID, Seemin Kashif, Saba Liaqat, Asma Afreen
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background Metabolic syndrome (MetS) being a biological abnormality confers the highest risk of type 2 diabetes mellitus (T2DM). Aim To assess MetS indicators in the newly diagnosed T2DM Pakistani population. Methods A cross-sectional study ( N = 123) with newly diagnosed T2DM patients (gender: both, MeanAge: 49.24 ± 6.84 years) was selected from Medical OPD, Pakistan Institute of Medical Sciences, Islamabad. Basic profile, family history, and physical activity were recorded through a predesigned questionnaire, dietary intake through seven days Food Diary and Food Frequency Questionnaire. Blood pressure and selected clinical signs and symptoms were recorded. Anthropometric measurements included mid-upper arm circumference (MUAC), body mass index (BMI), waist circumference (WC), waist-and-hip ratio (WHR), waist-to-height ratio (WHtR), and conicity index. Lab parameters included fasting blood glucose, HbA1c, insulin levels, and lipid profile. Homeostatic model assessment of insulin resistance (HOMA-IR) was computed to assess insulin resistance. Results Almost all parameters related to MetS were higher than normal. The prevalence of MetS was 59.7%. BMI, MUAC, and WHtR were independently associated with HOMA-IR, but WC, WHR, and the conicity index had no relationship MetS indicators. Conclusion The prevalence rate of MetS was found to be 59.7% in newly diagnosed T2DM patients. MUAC was found to be a better parameter for the diagnosis of central obesity and insulin resistance in the selected population.