Published in

American Medical Association, JAMA Dermatology, 2023

DOI: 10.1001/jamadermatol.2023.4445



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The Best Psoriasis Medications Emerge

Journal article published in 2023 by Andrew Blauvelt, Megan H. Noe
Distributing this paper is prohibited by the publisher
Distributing this paper is prohibited by the publisher

Full text: Unavailable

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Data provided by SHERPA/RoMEO


Clinical QuestionWhat are the most effective systemic medications to treat plaque psoriasis?Bottom LineThe most effective drugs for psoriasis were infliximab, bimekizumab, ixekizumab, and risankizumab, and the clinical effectiveness was similar when these 4 drugs were compared against one another. No statistically significant differences in serious adverse events were identified in any of the drugs compared with placebo. The main limitations of this meta-analysis include the lack of assessment of clinical effectiveness beyond 52 weeks and the lack of safety assessments for nonserious adverse events.