Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 9(66), 2022
DOI: 10.1128/aac.00527-22
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Mechanistic Insights to Combating NDM- and CTX-M-Coproducing Klebsiella pneumoniae by Targeting Cell Wall Synthesis and Outer Membrane Integrity
Journal article published in 2022 by
Nicholas M. Smith 
,
Katie Rose Boissonneault,
Liang Chen ,
Vidmantas Petraitis ,
Ruta Petraitiene ,
Xun Tao,
Jieqiang Zhou,
Yinzhi Lang,
Povilas Kavaliauskas,
Zackery P. Bulman ,
Patricia N. Holden,
Raymond Cha,
Jürgen B. Bulitta ,
Barry N. Kreiswirth ,
Thomas J. Walsh
and other authors.
,
Katie Rose Boissonneault,
Liang Chen ,
Vidmantas Petraitis ,
Ruta Petraitiene ,
Xun Tao,
Jieqiang Zhou,
Yinzhi Lang,
Povilas Kavaliauskas,
Zackery P. Bulman ,
Patricia N. Holden,
Raymond Cha,
Jürgen B. Bulitta ,
Barry N. Kreiswirth ,
Thomas J. Walsh
and other authors.
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
Metallo-β-lactamase (MBL)-producing Gram-negative bacteria cause infections associated with high rates of morbidity and mortality. Currently, a leading regimen to treat infections caused by MBL-producing bacteria is aztreonam combined with ceftazidime-avibactam.