Published in
Royal Society of Chemistry, Organic and Biomolecular Chemistry, 7(19), p. 1620-1625, 2021
DOI: 10.1039/d0ob02395g
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Biocatalytic oxidation of alcohols using galactose oxidase and a manganese(iii) activator for the synthesis of islatravir
Journal article published in 2021 by
Heather C. Johnson 
,
Shaoguang Zhang ,
Anna Fryszkowska ,
Serge Ruccolo ,
Sandra A. Robaire,
Artis Klapars,
Niki R. Patel ,
Aaron M. Whittaker ,
Mark A. Huffman ,
Neil A. Strotman
,
Shaoguang Zhang ,
Anna Fryszkowska ,
Serge Ruccolo ,
Sandra A. Robaire,
Artis Klapars,
Niki R. Patel ,
Aaron M. Whittaker ,
Mark A. Huffman ,
Neil A. Strotman
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Abstract
Manganese(iii) acetate activates galactose oxidase (GOase), a Cu-dependent metalloenzyme that catalyzes the oxidation of alcohols to aldehydes.