Climate change is a global threat to the food and nutritional security of the world. As greenhouse-gas emissions in the atmosphere are increasing, the temperature is also rising due to the greenhouse effect. The average global temperature is increasing continuously and is predicted to rise by 2 °C until 2100, which would cause substantial economic losses at the global level. The concentration of CO2, which accounts for a major proportion of greenhouse gases, is increasing at an alarming rate, and has led to higher growth and plant productivity due to increased photosynthesis, but increased temperature offsets this effect as it leads to increased crop respiration rate and evapotranspiration, higher pest infestation, a shift in weed flora, and reduced crop duration. Climate change also affects the microbial population and their enzymatic activities in soil. This paper reviews the information collected through the literature regarding the issue of climate change, its possible causes, its projection in the near future, its impact on the agriculture sector as an influence on physiological and metabolic activities of plants, and its potential and reported implications for growth and plant productivity, pest infestation, and mitigation strategies and their economic impact.