Background:A new instrument for measuring of disease activity in gout is a 4-variable gout disease activity score (GAS), announced in 2016 (1). GAS calculates self-reported number of attacks in the last year, patient visual analogue scale (VAS) for gout severity, serum uric acid level (mg/dL) and the number of tophi, and has shown good psychometric properties (1).Objectives:to test GAS in patients with gout and to evaluate its construct and convergent validityMethods:74 patients with gout were evaluated successively, as they entered the Institute of Rheumatology in Belgrade. Construct validity was assessed by associationos between GAS and SF-36, using Spearman’s rank correlation coefficients. Convergent validity was evaluated by testing the ability of the GAS score to distinguish between patients grouped by perceived disease severity, perceived general health and physicians perceived disease severity by using Kruskal–Wallis one-way analysis of variance. Computer statistic program SPSS 20.0 was used for data evaluation.Results:For the construct validity, significant correlations were found between GAS and SF-36 subscales, specially for Body pain (r=-0.725), Physical functioning (r=-0.684) and Physical limitations (r=-0.563), whereas Social functioning, Mental health, and Vitality were less affected. Correlation between GAS and Physical component scale of the SF-36 was the most prominent (r=-0.780). For the convergent validity, significant differences in GAS scores were found between patients grouped by perceived general health (p<0,01) and perceived disease severity (p<0,01), and by doctors perceived disease severity (p<0,01), demonstrating the ability of the GAS to distinguish between subgroups of patients.Conclusion:GAS has shown good psyshometric properties in Serbian cohort of patients and has proved to be valid and reliable tool for use in clinical practice.References:[1]Scirè CA, Carrara G, Viroli C, Cimmino MA, Taylor WJ, Manara M, Govoni M, Salaffi F, Punzi L, Montecucco C, Matucci-Cerinic M, Minisola G; Study Group for the Kick-Off of the Italian Network for Gout Study. Development and First Validation of a Disease Activity Score for Gout. Arthritis Care Res (Hoboken). 2016 Oct;68(10):1530-7.Table 1.Characteristics of the examined patientsPatient characteristicsMeanStd deviation95% ConfidenceIntervalAge (yrs)59,2710,2256,90-61,51Disease duration (yrs)8,757,727,01-10,49Number of attacks/last year3,893,743,08-4,71Weight (kg)91,44(17,14)86,52-96,37Height (cm)176,73(7,95)174,45-179-02Body Mass Index (kg/m2)29,14(4,1)27,96-30,32Waist circumference (cm)102,699,56100,35-105,05Systolic blood pressure135,4414,48130,43-140,50Diastolic blood pressure86.749.8682,31-89,22Serum urate level (µmol/ L)485,6102,09449,94-521,20No%Male7195,9Monoarthritis2939,2Olygoarthritis3142,1Polyarthritis1418,9Presence of tophi1723Disclosure of Interests:None declared