The current situation with COVID-19 is changing our courses of action toward ensuring health security. This is particularly crucial in airports, which usually receive more than 300,000 travellers in one single day. In this work, we present an Internet of Things (IoT) network to monitor the status of toilets and improve their maintenance. The system is based on IoT networks with different sensors to control soap levels, room capacity, distances, temperature, and humidity. This information is processed by a multi-agent system that detects possible anomalies and makes decisions accordingly. A case study in a real environment is developed in order to demonstrate the usefulness of the system. The results show that the proposed method can be used to successfully manage and control airport toilets.