This study analyzes the patterns of university co-authorship networks in the Guangdong-Hong Kong-Macau Greater Bay Area. It also examines the quality and subject distribution of co-authored articles within these networks. Social network analysis is used to outline the structure and evolution of the networks that have produced co-authored articles at universities in the Greater Bay Area from 2014 to 2018, at both regional and institutional levels. Field-weighted citation impact (FWCI) is used to analyze the quality and citation impact of co-authored articles in different subject fields. The findings of the study reveal that university co-authorship networks in the Greater Bay Area are still dispersed, and their disciplinary development is unbalanced. The study also finds that, while the research areas covered by high-quality co-authored articles fit the strategic needs of technological innovation and industrial distribution in the Greater Bay Area, high-quality research collaboration in the humanities and social sciences is insufficient.