ABSTRACT Using the largest mosaic of Hubble Space Telescope images around a galaxy cluster, we map the distribution of dark matter throughout an ∼6 × 6 Mpc2 area centred on the cluster MS 0451−03 (z = 0.54, $M_{200}=1.65\times 10^{15}\, {\rm M}_{⊙ }$). Our joint strong- and weak-lensing analysis shows three possible filaments extending from the cluster, encompassing six group-scale substructures. The dark matter distribution in the cluster core is elongated, consists of two distinct components, and is characterized by a concentration parameter of c200 = 3.79 ± 0.36. By contrast, XMM–Newton observations show the gas distribution to be more spherical, with excess entropy near the core, and a lower concentration of $c_{200}=2.35^{+0.89}_{-0.70}$ (assuming hydrostatic equilibrium). Such a configuration is predicted in simulations of major mergers 2–7 Gyr after the first core passage, when the two dark matter haloes approach second turnaround, and before their gas has relaxed. This post-merger scenario finds further support in optical spectroscopy of the cluster’s member galaxies, which shows that star formation was abruptly quenched 5 Gyr ago. MS 0451−03 will be an ideal target for future studies of the growth of structure along filaments, star formation processes after a major merger, and the late-stage evolution of cluster collisions.