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American Society of Hematology, Blood Advances, 9(4), p. 1859-1866, 2020

DOI: 10.1182/bloodadvances.2019001325

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Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Key Points Diagnostic and relapse diffuse large B-cell lymphoma (DLBCL) biopsies reveal increased mutational burden/loss of heterozygosity in HLA-A. Serially sampled tumor biopsies provide insight into therapeutic targets and evolutionary divergence in relapsed/refractory DLBCL.