Published in
American Association for the Advancement of Science, Science Translational Medicine, 530(12), 2020
DOI: 10.1126/scitranslmed.aay4447
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JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function
Journal article published in 2020 by
Susanne Adam 
,
Nils Simon ,
Ulrike Steffen ,
Fabian T. Andes,
Carina Scholtysek ,
Dorothea I. H. Müller,
Daniela Weidner,
Darja Andreev,
Arnd Kleyer ,
Stephan Culemann,
Madelaine Hahn,
Georg Schett ,
Gerhard Krönke ,
Silke Frey ,
Axel J. Hueber
,
Nils Simon ,
Ulrike Steffen ,
Fabian T. Andes,
Carina Scholtysek ,
Dorothea I. H. Müller,
Daniela Weidner,
Darja Andreev,
Arnd Kleyer ,
Stephan Culemann,
Madelaine Hahn,
Georg Schett ,
Gerhard Krönke ,
Silke Frey ,
Axel J. Hueber
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Abstract
JAK inhibition enhances the function of bone-forming osteoblasts, increases bone mass, and induces repair of arthritic bone erosions.