Published in
Royal Society of Chemistry, Chemical Science, 12(11), p. 3268-3280, 2020
DOI: 10.1039/d0sc00078g
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Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery
Journal article published in 2020 by
Gayathri R. Ediriweera,
Joshua D. Simpson 
,
Adrian V. Fuchs,
Taracad K. Venkatachalam,
Matthias Van De Walle,
Christopher B. Howard ,
Stephen M. Mahler,
James P. Blinco ,
Nicholas L. Fletcher ,
Zachary H. Houston ,
Craig A. Bell ,
Kristofer J. Thurecht
,
Adrian V. Fuchs,
Taracad K. Venkatachalam,
Matthias Van De Walle,
Christopher B. Howard ,
Stephen M. Mahler,
James P. Blinco ,
Nicholas L. Fletcher ,
Zachary H. Houston ,
Craig A. Bell ,
Kristofer J. Thurecht
This paper is made freely available by the publisher.
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Abstract
There remain several key challenges to existing therapeutic systems for cancer therapy, such as quantitatively determining the true, tissue-specific drug release profile in vivo, as well as reducing side-effects for an increased standard of care.