Published in
Royal Society of Chemistry, RSC Advances, 15(10), p. 8853-8865, 2020
DOI: 10.1039/d0ra00318b
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Rhenium(i) complexation–dissociation strategy for synthesising fluorine-18 labelled pyridine bidentate radiotracers
Journal article published in 2020 by
Mitchell A. Klenner 
,
Bo Zhang ,
Gianluca Ciancaleoni ,
James K. Howard ,
Helen E. Maynard-Casely ,
Jack K. Clegg ,
Massimiliano Massi ,
Benjamin H. Fraser ,
Giancarlo Pascali
,
Bo Zhang ,
Gianluca Ciancaleoni ,
James K. Howard ,
Helen E. Maynard-Casely ,
Jack K. Clegg ,
Massimiliano Massi ,
Benjamin H. Fraser ,
Giancarlo Pascali
This paper is made freely available by the publisher.
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Abstract
A novel fluorine-18 radiolabelling method employing rhenium(i) mediation is described herein. In less than 1 minute, fluorine-18 labelled complexes and ligands were synthesised in greater than 80% and 60% radiochemical yields (RCY), respectively.