Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 3(64), 2020
DOI: 10.1128/aac.02176-19
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Synergistic Activity of Exebacase (CF-301) in Addition to Daptomycin against Staphylococcus aureus in a Neutropenic Murine Thigh Infection Model
Journal article published in 2019 by
Tomefa E. Asempa,
Kamilia Abdelraouf,
Teresa Carabeo,
Raymond Schuch 
,
David P. Nicolau
,
David P. Nicolau
This paper was not found in any repository, but could be made available legally by the author.
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Abstract
We evaluated the efficacy of escalating doses of exebacase administered with subtherapeutic daptomycin exposures against 8 Staphylococcus aureus isolates in a neutropenic murine thigh infection model. Daptomycin alone resulted in mean growth of 0.39 ± 1.19 log 10 CFU/thigh.