Published in
American Association for the Advancement of Science, Science Advances, 10(5), 2019
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BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential
Journal article published in 2019 by
S. Miah 
,
C. A. S. Banks,
Y. Ogunbolude ,
E. T. Bagu,
J. M. Berg,
A. Saraf,
T. T. Tettey,
G. Hattem ,
G. Dayebgadoh,
C. G. Kempf,
M. Sardiu,
S. Napper,
L. Florens ,
K. E. Lukong ,
M. P. Washburn
,
C. A. S. Banks,
Y. Ogunbolude ,
E. T. Bagu,
J. M. Berg,
A. Saraf,
T. T. Tettey,
G. Hattem ,
G. Dayebgadoh,
C. G. Kempf,
M. Sardiu,
S. Napper,
L. Florens ,
K. E. Lukong ,
M. P. Washburn
This paper is made freely available by the publisher.
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Abstract
BRK phosphorylates and targets SMAD4 for proteasomal degradation to regulate aspects of the epithelial-mesenchymal transition.