Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

Nalls, Mike A.; von Coelln, Rainer; Blauwendraat, Cornelis; Vallerga, Costanza L.; Heilbron, Karl; Bandres-Ciga, Sara; Chang, Diana; Tan, Manuela; Kia, Demis A.; Noyce, Alastair J.; Xue, Angli; Bras, Jose; Young, Emily; Simón-Sánchez, Javier; Schulte, Claudia; Sharma, Manu; Krohn, Lynne; Pihlstrøm, Lasse; Siitonen, Ari; Iwaki, Hirotaka; Leonard, Hampton; Faghri, Faraz; Gibbs, J. Raphael; Hernandez, Dena G.; Scholz, Sonja W.; Botia, Juan A.; Martinez, Maria; Corvol, Jean-Christophe; Shulman, Lisa M.; Lesage, Suzanne; Jankovic, Joseph; Sutherland, Margaret; Tienari, Pentti; Majamaa, Kari; Toft, Mathias; Andreassen, Ole A.; Bangale, Tushar; Brice, Alexis; Yang, Jian; Gan-Or, Ziv; Gasser, Thomas; Heutink, Peter; Shulman, Joshua M.; Wood, Nicholas W.; Hinds, David A.; Hardy, John A.; Morris, Huw R.; Gratten, Jacob; Visscher, Peter M.; Graham, Robert R.; Singleton, Andrew B.; Adarmes-Gómez, Astrid D.; Aguilar, Miquel; Aitkulova, Akbota; Akhmetzhanov, Vadim; Alcalay, Roy N.; Alvarez, Ignacio; Alvarez, Victoria; Barrero, Francisco Javier; Bergareche Yarza, Jesús Alberto; Bernal-Bernal, Inmaculada; Billingsley, Kimberley; Blazquez, Marta; Bonilla-Toribio, Marta; Botía, Juan A.; Boungiorno, María Teresa; Brockmann, Kathrin; Bubb, Vivien; Buiza-Rueda, Dolores; Cámara, Ana; Carrillo, Fátima; Carrión-Claro, Mario; Cerdan, Debora; Chelban, Viorica; Clarimón, Jordi; Clarke, Carl; Compta, Yaroslau; Cookson, Mark R.; Craig, David W.; Danjou, Fabrice; Diez-Fairen, Monica; Dols-Icardo, Oriol; Duarte, Jacinto; Duran, Raquel; Escamilla-Sevilla, Francisco; Escott-Price, Valentina; Ezquerra, Mario; Feliz, Cici; Fernández, Manel; Fernández-Santiago, Rubén; Finkbeiner, Steven; Foltynie, Thomas; Garcia, Ciara; García-Ruiz, Pedro; Gomez Heredia, Maria Jose; Gómez-Garre, Pilar; González, Manuel Menéndez; Gonzalez-Aramburu, Isabel; Guelfi, Sebastian; Guerreiro, Rita; Hardy, John; Hassin-Baer, Sharon; Hoenicka, Janet; Holmans, Peter; Houlden, Henry; Infante, Jon; Jesús, Silvia; Jimenez-Escrig, Adriano; Kaishybayeva, Gulnaz; Kaiyrzhanov, Rauan; Karimova, Altynay; Kinghorn, Kerri J.; Koks, Sulev; Kulisevsky, Jaime; Labrador-Espinosa, Miguel A.; Leonard, Hampton L.; Lewis, Patrick; Lopez-Sendon, Jose Luis; Lovering, Ruth; Lubbe, Steven; Lungu, Codrin; Macias, Daniel; Manzoni, Claudia; Marín, Juan; Marinus, Johan; Marti, Maria Jose; Martínez Torres, Irene; Martínez-Castrillo, Juan Carlos; Mata, Marina; Mencacci, Niccolo E.; Méndez-Del-Barrio, Carlota; Middlehurst, Ben; Mínguez, Adolfo; Mir, Pablo; Mok, Kin Y.; Muñoz, Esteban; Narendra, Derek; Ojo, Oluwadamilola O.; Okubadejo, Njideka U.; Pagola, Ana Gorostidi; Pastor, Pau; Perez Errazquin, Francisco; Periñán-Tocino, Teresa; Pihlstrom, Lasse; Plun-Favreau, Helene; Quinn, John; R'Bibo, Lea; Reed, Xylena; Rezola, Elisabet Mondragon; Rizig, Mie; Rizzu, Patrizia; Robak, Laurie; Rodriguez, Antonio Sanchez; Rouleau, Guy A.; Ruiz-Martínez, Javier; Ruz, Clara; Ryten, Mina; Sadykova, Dinara; Schreglmann, Sebastian; Shashkin, Chingiz; Sierra, María; Suarez-Sanmartin, Esther; Taba, Pille; Tabernero, Cesar; Tan, Manuela X.; Tartari, Juan Pablo; Tejera-Parrado, Cristina; Tolosa, Eduard; Trabzuni, Daniah; Valldeoriola, Francesc; van Hilten, Jacobus J.; Van Keuren-Jensen, Kendall; Vargas-González, Laura; Vela, Lydia; Vives, Francisco; Williams, Nigel; Zharkinbekova, Nazira; Zharmukhanov, Zharkyn; Zholdybayeva, Elena; Zimprich, Alexander; Ylikotila, Pauli; Reich, Stephen; Savitt, Joseph; Agee, Michelle; Alipanahi, Babak; Auton, Adam; Bell, Robert K.; Bryc, Katarzyna; Elson, Sarah L.; Fontanillas, Pierre; Furlotte, Nicholas A.; Huber, Karen E.; Hicks, Barry; Jewett, Ethan M.; Jiang, Yunxuan; Kleinman, Aaron; Lin, Keng-Han; Litterman, Nadia K.; McCreight, Jennifer C.; McIntyre, Matthew H.; McManus, Kimberly F.; Mountain, Joanna L.; Noblin, Elizabeth S.; Northover, Carrie A. M.; Pitts, Steven J.; Poznik, G. David; Sathirapongsasuti, J. Fah; Shelton, Janie F.; Shringarpure, Suyash; Tian, Chao; Tung, Joyce; Vacic, Vladimir; Wang, Xin; Wilson, Catherine H.; Anderson, Tim; Bentley, Steven; Dalrymple-Alford, John; Fowdar, Javed; Halliday, Glenda; Henders, Anjali K.; Hickie, Ian; Kassam, Irfahan; Kennedy, Martin; Kwok, John; Lewis, Simon; Mellick, George; Montgomery, Grant; Pearson, John; Pitcher, Toni; Sidorenko, Julia; Silburn, Peter A.; Wallace, Leanne; Wray, Naomi R.; Zhang, Futao

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Manuela Tan
Nalls et al., 2019

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Elsevier, The Lancet Neurology, 12(18), p. 1091-1102, 2019

DOI: 10.1016/s1474-4422(19)30320-5

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@article{Nalls2019,
  author = {Nalls, Mike A. and von Coelln, Rainer and Blauwendraat, Cornelis and Vallerga, Costanza L. and Heilbron, Karl and Bandres-Ciga, Sara and Chang, Diana and Tan, Manuela and Kia, Demis A. and Noyce, Alastair J. and Xue, Angli and Bras, Jose and Young, Emily and Simón-Sánchez, Javier and Schulte, Claudia and Sharma, Manu and Krohn, Lynne and Pihlstrøm, Lasse and Siitonen, Ari and Iwaki, Hirotaka and Leonard, Hampton and Faghri, Faraz and Gibbs, J. Raphael and Hernandez, Dena G. and Scholz, Sonja W. and Botia, Juan A. and Martinez, Maria and Corvol, Jean-Christophe and Shulman, Lisa M. and Lesage, Suzanne and Jankovic, Joseph and Sutherland, Margaret and Tienari, Pentti and Majamaa, Kari and Toft, Mathias and Andreassen, Ole A. and Bangale, Tushar and Brice, Alexis and Yang, Jian and Gan-Or, Ziv and Gasser, Thomas and Heutink, Peter and Shulman, Joshua M. and Wood, Nicholas W. and Hinds, David A. and Hardy, John A. and Morris, Huw R. and Gratten, Jacob and Visscher, Peter M. and Graham, Robert R. and Singleton, Andrew B. and Adarmes-Gómez, Astrid D. and Aguilar, Miquel and Aitkulova, Akbota and Akhmetzhanov, Vadim and Alcalay, Roy N. and Alvarez, Ignacio and Alvarez, Victoria and Barrero, Francisco Javier and Bergareche Yarza, Jesús Alberto and Bernal-Bernal, Inmaculada and Billingsley, Kimberley and Blazquez, Marta and Bonilla-Toribio, Marta and Botía, Juan A. and Boungiorno, María Teresa and Brockmann, Kathrin and Bubb, Vivien and Buiza-Rueda, Dolores and Cámara, Ana and Carrillo, Fátima and Carrión-Claro, Mario and Cerdan, Debora and Chelban, Viorica and Clarimón, Jordi and Clarke, Carl and Compta, Yaroslau and Cookson, Mark R. and Craig, David W. and Danjou, Fabrice and Diez-Fairen, Monica and Dols-Icardo, Oriol and Duarte, Jacinto and Duran, Raquel and Escamilla-Sevilla, Francisco and Escott-Price, Valentina and Ezquerra, Mario and Feliz, Cici and Fernández, Manel and Fernández-Santiago, Rubén and Finkbeiner, Steven and Foltynie, Thomas and Garcia, Ciara and García-Ruiz, Pedro and Gomez Heredia, Maria Jose and Gómez-Garre, Pilar and González, Manuel Menéndez and Gonzalez-Aramburu, Isabel and Guelfi, Sebastian and Guerreiro, Rita and Hardy, John and Hassin-Baer, Sharon and Hoenicka, Janet and Holmans, Peter and Houlden, Henry and Infante, Jon and Jesús, Silvia and Jimenez-Escrig, Adriano and Kaishybayeva, Gulnaz and Kaiyrzhanov, Rauan and Karimova, Altynay and Kinghorn, Kerri J. and Koks, Sulev and Kulisevsky, Jaime and Labrador-Espinosa, Miguel A. and Leonard, Hampton L. and Lewis, Patrick and Lopez-Sendon, Jose Luis and Lovering, Ruth and Lubbe, Steven and Lungu, Codrin and Macias, Daniel and Manzoni, Claudia and Marín, Juan and Marinus, Johan and Marti, Maria Jose and Martínez Torres, Irene and Martínez-Castrillo, Juan Carlos and Mata, Marina and Mencacci, Niccolo E. and Méndez-Del-Barrio, Carlota and Middlehurst, Ben and Mínguez, Adolfo and Mir, Pablo and Mok, Kin Y. and Muñoz, Esteban and Narendra, Derek and Ojo, Oluwadamilola O. and Okubadejo, Njideka U. and Pagola, Ana Gorostidi and Pastor, Pau and Perez Errazquin, Francisco and Periñán-Tocino, Teresa and Pihlstrom, Lasse and Plun-Favreau, Helene and Quinn, John and R'Bibo, Lea and Reed, Xylena and Rezola, Elisabet Mondragon and Rizig, Mie and Rizzu, Patrizia and Robak, Laurie and Rodriguez, Antonio Sanchez and Rouleau, Guy A. and Ruiz-Martínez, Javier and Ruz, Clara and Ryten, Mina and Sadykova, Dinara and Schreglmann, Sebastian and Shashkin, Chingiz and Sierra, María and Suarez-Sanmartin, Esther and Taba, Pille and Tabernero, Cesar and Tan, Manuela X. and Tartari, Juan Pablo and Tejera-Parrado, Cristina and Tolosa, Eduard and Trabzuni, Daniah and Valldeoriola, Francesc and van Hilten, Jacobus J. and Van Keuren-Jensen, Kendall and Vargas-González, Laura and Vela, Lydia and Vives, Francisco and Williams, Nigel and Zharkinbekova, Nazira and Zharmukhanov, Zharkyn and Zholdybayeva, Elena and Zimprich, Alexander and Ylikotila, Pauli and Reich, Stephen and Savitt, Joseph and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K. and Bryc, Katarzyna and Elson, Sarah L. and Fontanillas, Pierre and Furlotte, Nicholas A. and Huber, Karen E. and Hicks, Barry and Jewett, Ethan M. and Jiang, Yunxuan and Kleinman, Aaron and Lin, Keng-Han and Litterman, Nadia K. and McCreight, Jennifer C. and McIntyre, Matthew H. and McManus, Kimberly F. and Mountain, Joanna L. and Noblin, Elizabeth S. and Northover, Carrie A. M. and Pitts, Steven J. and Poznik, G. David and Sathirapongsasuti, J. Fah and Shelton, Janie F. and Shringarpure, Suyash and Tian, Chao and Tung, Joyce and Vacic, Vladimir and Wang, Xin and Wilson, Catherine H. and Anderson, Tim and Bentley, Steven and Dalrymple-Alford, John and Fowdar, Javed and Halliday, Glenda and Henders, Anjali K. and Hickie, Ian and Kassam, Irfahan and Kennedy, Martin and Kwok, John and Lewis, Simon and Mellick, George and Montgomery, Grant and Pearson, John and Pitcher, Toni and Sidorenko, Julia and Silburn, Peter A. and Wallace, Leanne and Wray, Naomi R. and Zhang, Futao},
  doi = {10.1016/s1474-4422(19)30320-5},
  journal = {The Lancet Neurology},
  month = {dec},
  pages = {1091-1102},
  title = {Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies},
  url = {https://oadoi.org/10.1016/s1474-4422(19)30320-5},
  volume = {18},
  year = {2019}
}

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