American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 12(63), 2019
DOI: 10.1128/aac.01426-19
Full text: Unavailable
Metallo-β-lactamase (MBL)-producing Enterobacteriaceae , particularly those that coharbor serine β-lactamases, are a serious emerging public health threat given their rapid dissemination and the limited number of treatment options. Preclinical and anecdotal clinical data support the use of aztreonam in combination with ceftazidime-avibactam against these pathogens, but other aztreonam-based combinations have not been explored.