American Society of Hematology, Blood Advances, 21(3), p. 3248-3260, 2019
DOI: 10.1182/bloodadvances.2019000703
Full text: Download
Key PointsA trimeric extracellular moiety of APRIL has enhanced binding to BCMA and TACI compared with monomeric APRIL when incorporated into a CAR. T cells transduced with a trimeric APRIL-based CAR are a promising approach for the treatment of MM.